Hyaluronic acid (HA) is a natural skin component that maintains moisture, firmness and elasticity. Over time—and with factors like sun exposure—your body’s HA levels decline, leading to dryness, thinning, loss of suppleness and the formation of lines, wrinkles and volume loss. NEURAMIS™ fillers replenish HA to restore hydration, smoothness and facial harmony.
Formulation
- HA Concentration: 24 mg/mL
- Lidocaine: 0.3% for patient comfort
- pH Buffer: Physiological phosphate
Product Variants & Indications
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NEURAMIS™ (Superficial Lines)
- Particle Size: Smallest
- Injection Depth: Superficial dermis
- Uses: Very fine wrinkles—worry lines, periorbital and perioral lines
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NEURAMIS™ Deep (Moderate Wrinkles)
- Particle Size: Medium
- Injection Depth: Mid-dermis
- Uses: Moderate lines—glabellar folds, oral commissures, lip contour
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NEURAMIS™ Volume (Deep Folds & Contours)
- Particle Size: Largest
- Injection Depth: Deep dermis or superficial subcutis
- Uses: Deep folds—nasolabial and marionette lines; lip plumping; cheek and chin contouring
Areas of Treatment
- Cheeks & cheekbones
- Chin enhancement
- Nasolabial folds & marionette lines
- Forehead and other fine wrinkles
- Lip contouring & plumping
Administration & Protocol
- Injection Depth: Mid to deep dermis (per variant)
- Technique: Linear thread or small bolus
- Treatment Interval: Every 3–6 months, per patient needs
Efficacy & Duration
- Onset: Immediate hydration and subtle lift
- Duration: 6–12 months (varies by product and patient factors)
Storage & Handling
- Temperature: 2–25 °C; avoid freezing, heat and direct sunlight
- Shelf Life: 24 months from manufacture
- Packaging: 1 mL prefilled syringe
Safety Profile
NEURAMIS™ is biocompatible and fully biodegradable. Lidocaine minimizes injection discomfort. Common, transient side effects may include redness, swelling or bruising. Administer only by qualified healthcare professionals.
Disclaimer:
Bruno Dermal Filler products are strictly intended for use by licensed medical and aesthetic professionals. Not suitable for self-administration or use by untrained individuals.
